Cas9 / Anti-CRISPR-associated endonuclease Cas9/Csn1 antibody

CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids) (PubMed: 21455174). Cas9 only stabilizes the pre-crRNA: tracrRNA interaction and has no catalytic function in RNA processing (PubMed:24270795). Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA).

PhytoAB has PHY0361S antibody for Cas9, the immunogen is KLH-conjugated synthetic peptide of Cas9 derived from Streptococcus pyogenes M1 GAS AAK33936.1.

For more species homologues information, please contact tech support at tech@phytoab.com.