Other Antibodies
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Starting at $89.00
Immunogen: AAK33936.1 Q99ZW2 Synonyms: Cas9, SpCas9, SpyCas9 Background:
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids) (PubMed: 21455174). Cas9 only stabilizes the pre-crRNA: tracrRNA interaction and has no catalytic function in RNA processing (PubMed:24270795). Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA).
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