FRO1 is a protein with high similarity to the 18-kD Fe-S subunit of complex I (NADH dehydrogenase, EC 1.6.5.3) in the mitochondrial electron transfer chain.
HRD1 are homologs of the yeast/human Hrd1 protein: AT3G16090 (Hrd1A), AT1G65040 (Hrd1B). They are involved in ERAD (Endoplasmic reticulum- associated degradation).
The 26S proteasome plays a central role in the degradation of regulatory proteins involved in a variety of developmental processes. It consists of two multisubunit protein complexes: the proteolytic core protease and the regulatory particle (RP).The RPN1 subunit belongs to the base complex of the RP and is known to physically interact with two proteins carrying ubiquitin-like domains, Rad23 and Dsk2.